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It hosts a vast selection of existing literature-based physiologically and pharmaceutically
relevant mechanistic models in standard formats. Our mission is to provide the systems
modelling community with reproducible, high-quality,
models published in the scientific literature. More information about using BioModels such as model submission, update, publication can be found in the FAQ.

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Zake2021 – PBPK model of metformin in mice and humans

It’s a simplified PBPK model used to study the metformin concentration-time profile in different tissues by applying some parameters from mice and other human tissue data.

Model(s) associated with this Model of the Month:





Last updated by: Krishna Kumar Tiwari